Materials in bionanotechnology and biomedical lab

The group is active in biomedical research, with particular emphasis on engineering in surgery, biomolecular, cellular and tissue engineering; controlled drug delivery; bioartificial systems and materials. The group is highly multidisciplinary with competences ranging from chemistry to materials science and biomedical engineering, and combines expertise in polymer synthesis, biomedicine, engineering and bionanotechnologies to design novel bioinspired constructs able to guide and induce specific biological responses.

The team is divided in 2 groups, working in two different laboratories located in Turin and Alessandria.

 

Projects

  • Selected funded research projects
    • ENGINEERED MULTI-WELL PLATFORMS INTEGRATING BIOCHEMICAL AND BIOPHYSICAL CUES FOR THE FUNCTIONAL MATURATION AND ELECTROPHYSIOLOGICAL MONITORING OF CARDIAC TISSUE MODELS (EMPATIC)
      CHIONO VALERIA
      2024 - 2025 (Current)
    • KITS FOR ADVANCED POLYMER-LIPID NANOCARRIERS FOR TARGETED DELIVERY OF RNAS TO CARDIAC AND SKELETAL MUSCLE CELLS
      CHIONO VALERIA
      2023 - 2025 (Current)
    • EXOCRINE GLANDULAR TISSUE MODELS THROUGH PRECISELY DESIGNED BIOMIMETIC ENVIRONMENTS: AN ENGINEERING TOOL TO IMPROVE UNDERSTANDING AND TREATMENT FOR PANCREATIC CANCER (ERATOSTHENES)
      CIARDELLI GIANLUCA
      2023 - 2025 (Current)
    • GREEN-MICROFLUIDIC PLATFORM FOR ADVANCED ORGAN ON CHIP CULTURES (GREEN-MID-PLACE)
      CARMAGNOLA IRENE
      2023 - 2025 (Current)
    • DESIGN AND VALIDATION OF AN ADVANCED DELIVERY SYSTEM FOR MIRNAS AND STEM CELL-DERIVED EXTRACELLULAR VESICLES FOR DIRECT CARDIAC REPROGRAMMING THROUGH A MECHANICALLY-STIMULATED HUMAN CARDIAC SCAR MODEL - DESIRE
      CHIONO VALERIA
      2023 - 2025 (Current)
    • SMART INJECTABLE HYDROGELS CARRYING MULTI-FUNCTIONAL NANO-SYSTEMS TO TACKLE CHRONIC WOUND BIOFILM THROUGH AN ANTIBIOTIC-FREE APPROACH
      CIARDELLI GIANLUCA
      2023 - 2025 (Current)
    • A 3D BIOPRINTED SPINAL CORD MODEL TO REACH FUNCTIONAL MEANINGFUL AND CLINICALLY TRANSLATABLE REGENERATION (3D-BIOSAME)
      TONDA TURO CHIARA
      2023 - 2025 (Current)
    • NANOPARTICELLE POLIMERICHE IBRIDE PER UNA TERAPIA CON RNA NELLA CURA DI PATOLOGIE CARDIACHE: SCALE-UP DELLA PRODUZIONE E VALIDAZIONE PRECLINICA (NAPTER)
      CHIONO VALERIA
      2023 - 2025 (Current)
    • RECOVERY: PRECISE CARDIAC ORGAN-ON-CHIP MODELING TO IMPROVE EXTRACELLULAR VESICLE-BASED PARACRINE THERAPY AGAINST MYOCARDIAL INJURY
      CHIONO VALERIA
      2023 - 2025 (Current)
    • A BIOPRINTED ALVEOLAR LUNG-ON-CHIP DEVICE TO ASSESS THE ROLE OF INHALED POLLUTANTS TOWARDS PULMONARY FIBROSIS ONSET
      CIARDELLI GIANLUCA
      2023 - 2025 (Current)
    • PLASMA-ACTIVATED HYDROGEL: NEW FRONTIERS SOLUTIONS IN CARDIAC REGENERATIVE MEDICINE
      CHIONO VALERIA
      2023 - 2025 (Current)
    • DEVELOPMENT OF A THERAPEUTIC STRATEGY TO SUPPRESS LSD1 AND PRMT6-MEDIATED TOXIC GAIN OF FUNCTION IN SBMA
      CHIONO VALERIA
      2023 - 2025 (Current)
    • NANOPARTICELLE POLIMERICHE IBRIDE PER UNA TERAPIA A BASE DI MICRORNA PER LA RIGENERAZIONE CARDIACA: PERCORSO DI AVVICINAMENTO ALL’APPLICAZIONE CLINICA (NANOCARD).
      CHIONO VALERIA
      2023 - 2024 (Current)
    • HUMAN MULTI-TISSUE PLATFORM FOR COMPREHENSIVE EVALUATION OF CHEMICAL TOXICOLOGY ON A CHIP
      CIARDELLI GIANLUCA
      2022 - 2024 (Current)
    • ENVIRONMENTAL TOXICITY CHEMICAL MIXTURES THROUGH AN INNOVATIVE PLATFORM BASED ON AGED CARDIAC TISSUE MODEL
      CIARDELLI GIANLUCA
      2021 - 2024 (Current)
    • NANOPARTICELLE POLIMERICHE IBRIDE PER UNA NUOVA GENERAZIONE DI VETTORI NON VIRALI PER TERAPIA GENICA NELLA RIGENERAZIONE CARDIACA (POLHYGENTH).
      CHIONO VALERIA
      2022 - 2023 (Current)
    • VISCO3DCELL- SVILUPPO DI UNA METODOLOGIA NON-INVASIVA PER LO STUDIO DELLE PROPRIETÀ VISCOELASTICHE DI COLTURE CELLULARI 3D.
      CHIONO VALERIA
      2021 - 2022 (Current)
    • CARATTERIZZAZIONE CHIMICO-FISICA E MORFOLOGICA PER DETERMINARE LA PRESENZA DI COLLAGENE E LIPIDI IN CAMPIONI
      CARMAGNOLA IRENE
      2022 - 2023 (Completed)
    • DIRECT CELL REPROGRAMMING THERAPY IN MYOCARDIAL REGENERATION THROUGH AN ENGINEERED MULTIFUNCTIONAL PLATFORM INTEGRATING BIOCHEMICAL INSTRUCTIVE CUES
      CHIONO VALERIA
      2018 - 2023 (Completed)
    • EVPRO - DEVELOPMENT OF EXTRACELLULAR VESICLES LOADED HYDROGEL COATINGS WITH IMMUNOMODULATORY ACTIVITY FOR PROMOTED REGENERATIVE OSSEOINTEGRATION OF REVISION ENDOPROSTHESIS
      CIARDELLI GIANLUCA
      2019 - 2022 (Completed)
    • CONVENZIONE OPERATIVA TRA POLITECNICO DI TORINO DIMEAS E CNR ISTITUTO PER I PROCESSI CHIMICO FISICI - IPCF DELLA CONVENZIONE QUADRO TRA CNR E POLITECNICO DI TORINO
      CIARDELLI GIANLUCA
      2018 - 2021 (Completed)
    • DIGITAI TECHNOLOGY FOR LUNG CANCER TREATMENT
      CIARDELLI GIANLUCA, PIRRI CANDIDO
      2018 - 2021 (Completed)
    • HYGLIO - THERANOSTIC INJECTABLE HYDROGEL FOR GLIOBLASTOMA
      CIARDELLI GIANLUCA
      2015 - 2019 (Completed)
    • HYMEDPOLY - DRUG-FREE ANTIBACTERIAL HYBRID BIOPOLYMERS FOR MEDICAL APPLICATIONS
      CIARDELLI GIANLUCA
      2015 - 2018 (Completed)
    • REBIOSTENT - REINFORCED BIORESORBABLE BIOMATERIALS FOR THERAPEUTIC DRUG ELUTING STENTS
      CIARDELLI GIANLUCA
      2014 - 2016 (Completed)
    • DESTINI - SVILUPPO DI UNA PIATTAFORMA DI STENT IN LEGA DI NITINOL (NICHEL-TITANIO) CON SUPERFICIE A RILASCIO DI FARMACO IDONEA AD APPLICAZIONI PER IL TRATTAMENTO DELL'ISCHEMIA CRONICA DEGLI ARTI INFERIORI
      CIARDELLI GIANLUCA
      2014 - 2016 (Completed)
    • INGEGNERIZZAZIONE DI MODELLI D'ORGANO DI INTERESSE FISIOLOGICO E PATOLOGICO PER L'INDAGINE DI DISTURBI LEGATI ALL'INVECCHIAMENTO. (MIND)
      CIARDELLI GIANLUCA
      2013 - 2016 (Completed)
    • BIO_GBR - BIOENGINEERED SCAFFOLD FOR GUIDED BONE REGENERATION
      CIARDELLI GIANLUCA
      2015 - 2015 (Completed)
    • CARATTERIZZAZIONE DI MATERIALI POLIURETANICI TERMOSENSIBILI PER APPLICAZIONE NEL RILASCIO DI FARMACI
      CIARDELLI GIANLUCA
      2014 - 2015 (Completed)
    • MATERIALI BIOARTIFICIALI E SCAFFOLD BIOMIMETICI PER LA TERAPIA A BASE DI CELLULE STAMINALI NELLA RIGENERAZIONE DEL MIOCARDIO
      CHIONO VALERIA
      2012 - 2015 (Completed)
    • ANALISI DELLE CARATTERISTICHE DI LINEE IN POLIVINILCLORURO PVC PER APPLICAZIONI IN EMODIALISI
      CIARDELLI GIANLUCA
      2014 - 2014 (Completed)
    • B3-BARRIER - DISPOSITIVI BIOARTIFICIALI E BIORIASSORBIBILI CON PROPRIETÀ BIOMIMETICHE E DI BARRIERA SELETTIVA PER LA CHIRURGIA RIGENERATIVA ORALE
      CIARDELLI GIANLUCA
      2012 - 2014 (Completed)
    • BICONERVE - BIOMIMETIC CONSTRUCTS FOR NERVE REGENERATION
      CIARDELLI GIANLUCA
      2011 - 2014 (Completed)
    • HERNAX - PROTESI AUTO-ADESIVA PER LA RIPARAZIONE DELLE ERNIE
      CIARDELLI GIANLUCA
      2011 - 2014 (Completed)
    • RIVESTIMENTI A BASE DI BIOPOLIMERI PER UN EFFICACE TRATTAMENTO DELLE FERITE (BIOPOLYMER BASED DRESSINGS FOR EFFICIENT WOUND MANAGEMENT-BIODRESS)
      CIARDELLI GIANLUCA
      2011 - 2013 (Completed)
    • NANOSTENT - MATERIALI E NANOTECNOLOGIE PER DISPOSITIVI ENDOVASCOLARI DI NUOVA GENERAZIONE
      CIARDELLI GIANLUCA
      2010 - 2013 (Completed)
    • MATERIALI BIOMIMETICI INGEGNERIZZATI PER LA RIGENERAZIONE DEI TESSUTI MUSCOLARI
      CIARDELLI GIANLUCA
      2010 - 2012 (Completed)
    • PROGRAMMA VIGONI (BANDO 2009) - PEPTIDE-FUNCTIONNALIZED POLYURETHENES STIMULATING CELL GROWTH, MIGRATION AND DIFFERENTIATION
      CIARDELLI GIANLUCA
      2010 - 2011 (Completed)
    • EVALUATION OF A NEW TENDONS REPAIR PROCEDURE
      CIARDELLI GIANLUCA
      2009 - 2010 (Completed)
    • MATERIALI INNOVATIVI E NANOSTRUTTURATI PER APPLICAZIONI TESSILI NEL SETTORE MEDICALE
      CIARDELLI GIANLUCA
      2009 - 2010 (Completed)
    • REPERIMENTO E CARATTERIZZAZIONE DI SPECIFIC MATERIALI POLIMERICI UTILIZZATI NELLA REALIZZAZIONE DI COPPA ACETABOLARI PER PROTESI D'ANCA
      CIARDELLI GIANLUCA
      2009 - 2010 (Completed)
    • PHOTONANOTECH - PHOTOZYME NANOPARTICLE APPLICATIONS FOR WATER PURIFICATION, TEXTILE FINISHING, PHOTODYNAMIC BIOMINARILIZATION AND BIOMATERIAL COATING
      CIARDELLI GIANLUCA
      2007 - 2010 (Completed)
    • RIGENERAZIONE DEL NERVO PERIFERICO MEDIANTE DISPOSITIVI BIOARTIFICIALI (RICERCA SANITARIA FINALIZZATA 2007)
      CIARDELLI GIANLUCA
      2007 - 2009 (Completed)
    • NUOVI POLIMERI BIOATTIVI DEGRADABILI NELLA PROGETTAZIONE DI SCAFFOLD MICROSTRUTTURATI PER LA PROLIFERAZIONE E DIFFERENZIAMENTO CELLULARE
      CIARDELLI GIANLUCA
      2006 - 2008 (Completed)
    • PARERE SULL'UTILIZZO DI MATERIALI INNOVATIVI NANOCOMPOSITI PER LA RIPARAZIONE DEI DIFETTI DELLA PARETE ADDOMINALE E DEL PAVIMENTO PELVICO IN BASE ALLE LORO PROPRIETÀ MECCANICHE E FUNZIONALI
      CIARDELLI GIANLUCA
      2007 - 2007 (Completed)
    • HIPERMAX - HIGH PERFORMANCE INDUSTRIAL PROTEIN MATRICES THROUGH BIOPROCESSING
      CIARDELLI GIANLUCA
      2005 - 2007 (Completed)

Publications