Bioreactors & transport phenomena unit

Bioreactors for cell culturing in Tissue Engineering and Regenerative Medicine applications

Design and fabrication of advanced bioreactors for basic cell and tissue research, drug discovery, in vitro personalized disease modelling, and cell-based personalized regenerative therapies. The bioreactor design is supported by computational tools that allow the development of the optimal geometries, the definition of the suitable operating culture conditions and quantitative analyses of mass transport and flow-induced shear stress.

Design and Characterization of Transport Phenomena in Scaffolds for Tissue Engineering and Regenerative Medicine Applications

Computational modeling of flow within image-based models of 3D porous scaffolds to (1) assess scaffold transport properties and performance (permeability, flow-induced shear stress, etc.) and (2) investigate the influence of interstitial flow.