Full Professor
Department of Mechanical and Aerospace Engineering (DIMEAS)
- Member of Interdepartmental Center PolitoBIOMed Lab - Biomedical Engineering Lab
- Substitute member Research Ethics Committee
Profile
Research interests
Biography
Valeria Chiono has a Master Degree cum laude in Chemical Engineering and a PhD in Chemical and Materials Engineering from the University of Pisa, Italy. She is currently Full Professor at the Department of Mechanical and Aerospace Engineering of Politecnico di Torino, Italy. Her research is aimed at the design of innovative bioengineering approaches to solve key problems in regenerative medicine and nanomedicine, and includes the development of bioactive materials and interfaces, tissue engineering, materials characterization, in vitro tissue models, drug delivery and non-viral gene therapy. One main research topic is cardiac tissue engineering. She has been the coordinator of several research projects, including STARIGEN FIRB2010 project, financed by the Italian Ministry of Education, University and Research, on the preparation of biomimetic scaffolds for cardiac regeneration. In 2017 she has been granted the ERC Consolidator project BIORECAR (contract number: 772168; http://www.biorecar.polito.it/) on advanced strategies for cardiac regeneration by direct reprogramming of fibroblasts into cardiomyocytes by an injectable hydrogel releasing miRNA-loaded nanoparticles. In BIORECAR in vitro models of fibrotic human cardiac tissue are also developed for preclinical investigation. Furthermore, she manages BIORECAR Cell Laboratory at Politecnico di Torino. She is the main lecturer of the following courses at the Faculty of Biomedical Engineering at Politecnico di Torino: “Engineering for regenerative medicine”, “Cell and tissue engineering” and “Laboratory of Tissues and Physiological Processes' Models”. In 2021, she has been appointed Vice-Director of Centro 3R. She is in the editorial board of journals such as Frontiers in Bioengineering and Biotechnology and Biomedical Materials. She is author of 122 scientific publications (H-index/citations: 31/4617 Scopus; 36/6253 Google Scholar) and 5 patents in the field of biomaterials, tissue engineering and nanomedicine.
Curriculum
Scientific branch
(Area 0009 - Industrial and information engineering)
Research topics
- Antimicrobial coatings based on bacterial biosurfactants or biomimetic strategies
- Cardiac tissue engineering: design of biomimetic scaffolds for a stem cells-based therapy in cardiac regeneration
- Design of biomimetic materials by the preparation of bioartificial blends or surface functionalization of synthetic polymer scaffolds with bioactive molecules.
- Direct cell reprogramming applied to cardiac regeneration: preparation of nanoparticles for oligonucleotide release and injectable hydrogels for an in situ therapy of infarcted cardiac tissue.
- Drug releasing hydrogels: preparation of hydrogels based on synthetic and/or natural polymers encapsulating drugs for a controlled and sustained release.
- In vitro tissue models: blood brain barrier and blood vessels on a chip; engineered cardiac fibrotic tissue; healthy and pathological (mimicking chronic wounds) skin tissue
- Non-viral gene therapy: lipid and/or polymer nanoparticles for the release of oligonucleotide agents (e.g., siRNAs and miRNAs)
- Preparation of systems for drug release by green technologies, making use of polymers prepared by bacterial fermentation on by-products of the food industry, or derived from waste products from agricolture, and avoiding or minimizing the use of organic solvents.
Skills
ERC sectors
SDG
Awards and Honors
- BioPmed Award 2014 - Gold conferred by BioPmed (2014)
- Back Cover in Advanced Healthcare Materials conferred by Advanced Healthcare Materials - Wiley (2020)
Fellowships
- Founding partner - ERC in ITALY, Italia (2021-)
- Steering Committe member - Centro Interuniversitario per la Promozione dei Principi delle 3R nella Didattica e nella Ricerca (Centro 3R), Italia (2019-)
- Founding partner - Gruppo Nazionale di Bioingegneria, Italia (2019-)
- Effective member - European Society of Cardiology (ESC), Europeo (2018-)
- Effective member - European Society for Biomaterials, ESB, Europeo (2018-)
- Effective member - TERMIS-EU, Europeo (2012-)
Editorial boards
- MICRO (2021-), Editorial board member
- FRONTIERS IN BIOMATERIALS SCIENCE (2021-), Other editorial activities
- FRONTIERS IN PHARMACOLOGY (2021-), Other editorial activities
- BIOMEDICAL MATERIALS (2020-), Editorial board member
- FRONTIERS IN CARDIOVASCULAR MEDICINE (2020-), Other editorial activities
- FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2018-), Associate Editor of magazine or editorial series
- 4 OPEN (2018-), Editorial board member
- BIOMEDICAL SCIENCE AND ENGINEERING (2016-), Director
Conferences
- I Convegno Nazionale SIOoC2023 (4/5/2023-5/5/2023), Program committee
- International Congress on Biofabrication 2022 (25/9/2022-28/9/2022), Program chair
- III Convegno Annuale "L'era delle 3R: modelli in silico, in vitro e in vivo per promuovere la ricerca traslazionale" (30/9/2021-1/10/2021), Chairman of the organizing committee
- XL Scuola Annuale di Bioingegneria 2021 “Biofabrication: an integrated bioengineering approach for the automated fabrication of biological structures for clinical and research applications” (13/9/2021-16/9/2021), Participation to the organizing committee
- CANCERTO - "Nanoscience in Cancer Immunotherapy" (9/3/2021-11/3/2021), Participation to the organizing committee
- Workshop “Biology and bioengineering tools in the treatment of H2020 age-related diseases”, Chairman of the organizing committee
- Workshop "Engineered Biomaterials and Biomedical Devices in the Regenerative Medicine of the Nervous System" (19/11/2015-20/11/2015), Chairman of the organizing committee
- CONGRESSO SOCIETÀ ITALIANA BIOMATERIALI 2013 (3/6/2013-5/6/2013), Participation to the organizing committee
Other titles
- Membro della Giunta DIMEAS 2019-2023 (2019-)
- Referente di Ateneo per l'Azione del PNRR: Centro Nazionale 3 "Sviluppo di terapia genica e farmaci con tecnologia a RNA" (2021-)
- Valutazione carriere per studenti che accedono alla Laurea Magistrale in Ingegneria Biomedica - Politecnico di Torino (2021-)
- Commissario per l'Abilitazione Scientifica Nazionale (ASN) - Settore Concorsuale 09/G2 - Bioingegneria (2021-)
- Tutor accademico di studenti Erasmus Incoming - Facoltà di Ingegneria Biomedica, Politecnico di Torino (2016-2021)
Research networks
Roles as evaluator or expert
- First Call of the ADMIRE Marie Skłodowska-Curie Action COFUND in Advanced Materials Research.. 2021
TRINITY COLLEGE DUBLIN - REMOTE REVIEW ERC GRANTS. 2021
ERC - EUROPEAN RESEARCH COUNCIL - EXECUTIVE AGENCY - REMOTE REVIEW ERC GRANTS. 2020
ERC - EUROPEAN RESEARCH COUNCIL - EXECUTIVE AGENCY
Non-commercial collaboration agreements
- Convenzione per il funzionamento del Centro Interuniversitario per la promozione dei principi delle 3R nella didattica e nella ricerca (CENTRO 3R), (periodo sconosciuto) - Responsabile contrattuale
Inter-university centres - Adesione al Centro Interuniversitario per la Promozione dei Principi delle 3R nella didattica e nella ricerca - CENTRO 3R, (2019-2023) - Responsabile Scientifico
Inter-university centres
Teaching
Collegi of the PhD programmes
- BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2022/2023 (39. ciclo)
Politecnico di TORINO - BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2021/2022 (38. ciclo)
Politecnico di TORINO - BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2020/2021 (37. ciclo)
Politecnico di TORINO - BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2019/2020 (36. ciclo)
Politecnico di TORINO - BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2018/2019 (35. ciclo)
Università degli Studi di TORINO - BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2017/2018 (34. ciclo)
Università degli Studi di TORINO - BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2016/2017 (33. ciclo)
Università degli Studi di TORINO - BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2015/2016 (32. ciclo)
Politecnico di TORINO - BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2014/2015 (31. ciclo)
Politecnico di TORINO - BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2013/2014 (30. ciclo)
Politecnico di TORINO
Collegi of the degree programmes
- Collegio di Ingegneria Biomedica. Componente
Teachings
PhD
- Molecular Regulation of Biomaterial, Cell/Tissue Interactions, Mechanisms to Prevent Implant Failure (didattica di eccellenza). A.A. 2022/23, BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE. Main teacher
- Terapie avanzate (nanomedicina, terapia genica e cellulare) in chirurgia. A.A. 2018/19, BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE. Teaching assistant
Master of Science
- Sistemi biomimetici. A.A. 2023/24, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Ingegneria per la medicina rigenerativa/Bioreattori (modulo di Ingegneria per la medicina rigenerativa). A.A. 2023/24, INGEGNERIA BIOMEDICA. Titolare del corso
- Laboratory of Tissues and Physiological Processes' Models. A.A. 2023/24, INGEGNERIA BIOMEDICA. Titolare del corso
- Sistemi biomimetici. A.A. 2022/23, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Ingegneria per la medicina rigenerativa/Bioreattori (modulo di Ingegneria per la medicina rigenerativa). A.A. 2022/23, INGEGNERIA BIOMEDICA. Titolare del corso
- Laboratory of Tissues and Physiological Processes' Models. A.A. 2022/23, INGEGNERIA BIOMEDICA. Titolare del corso
- Scuola GNB. A.A. 2021/22, INGEGNERIA BIOMEDICA. Titolare del corso
- Sistemi biomimetici. A.A. 2021/22, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Ingegneria per la medicina rigenerativa. A.A. 2021/22, INGEGNERIA BIOMEDICA. Titolare del corso
- Laboratory of Tissues and Physiological Processes' Models. A.A. 2021/22, INGEGNERIA BIOMEDICA. Titolare del corso
- Scuola GNB. A.A. 2020/21, INGEGNERIA BIOMEDICA. Titolare del corso
- Sistemi biomimetici. A.A. 2020/21, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Ingegneria per la medicina rigenerativa. A.A. 2020/21, INGEGNERIA BIOMEDICA. Titolare del corso
- Formazione pratica in nanotecnologie biomediche e terapie avanzate. A.A. 2020/21, INGEGNERIA BIOMEDICA. Collaboratore del corso
- New advances in alternative preclinical trials. A.A. 2020/21, INGEGNERIA BIOMEDICA. Titolare del corso
- Ingegneria per la medicina rigenerativa. A.A. 2019/20, INGEGNERIA BIOMEDICA. Titolare del corso
- Ingegneria per la medicina rigenerativa/Bioreattori (modulo di Ingegneria per la medicina rigenerativa). A.A. 2019/20, INGEGNERIA BIOMEDICA. Titolare del corso
- Formazione pratica in nanotecnologie biomediche e terapie avanzate. A.A. 2019/20, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Sistemi biomimetici. A.A. 2019/20, INGEGNERIA BIOMEDICA. Collaboratore del corso
- New advances in alternative preclinical trials. A.A. 2019/20, INGEGNERIA BIOMEDICA. Titolare del corso
- Frontiers in Bioengineering enabling nanotechnologies. A.A. 2018/19, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Sistemi biomimetici. A.A. 2018/19, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Ingegneria per la medicina rigenerativa/Bioreattori (modulo di Ingegneria per la medicina rigenerativa). A.A. 2018/19, INGEGNERIA BIOMEDICA. Titolare del corso
- Formazione pratica in nanotecnologie biomediche e terapie avanzate. A.A. 2018/19, INGEGNERIA BIOMEDICA. Collaboratore del corso
Bachelor of Science
- Ingegneria delle cellule e dei tessuti. A.A. 2023/24, INGEGNERIA BIOMEDICA. Titolare del corso
- Ingegneria delle cellule e dei tessuti. A.A. 2022/23, INGEGNERIA BIOMEDICA. Titolare del corso
- Ingegneria delle cellule e dei tessuti. A.A. 2021/22, INGEGNERIA BIOMEDICA. Titolare del corso
- Ingegneria delle cellule e dei tessuti. A.A. 2020/21, INGEGNERIA BIOMEDICA. Titolare del corso
- Ingegneria delle cellule e dei tessuti. A.A. 2019/20, INGEGNERIA BIOMEDICA. Titolare del corso
- Ingegneria delle cellule e dei tessuti. A.A. 2018/19, INGEGNERIA BIOMEDICA. Titolare del corso
Research
Research groups
Research projects
Projects funded by competitive calls
- NAPTER - Nanoparticelle polimeriche ibride per una terapia con RNA nella cura di patologie cardiache: scale-up della produzione e validazione preclinica (NAPTER) , (2023-2025) - Responsabile Scientifico
PNRR – Mission 4 - RECOVERY: pREcise Cardiac Organ-on-chip modeling to improve extracellular VEsicle-based paracrine therapy against myocaRdial Injury , (2023-2025) - Responsabile Scientifico
PNRR – Mission 4 - POLIRNA - Kits for advanced polymer-lipid nanocarriers for targeted delivery of RNAs to cardiac and skeletal muscle cells , (2023-2025) - Responsabile Scientifico
UE-funded research - HE - Excellent Science - ERC - DESIRE - Design and validation of an advanced delivery system for miRNAs and stem cell-derived extracellular vesicles for direct cardiac reprogramming through a mechanically-stimulated human cardiac scar model - DESIRE , (2023-2025) - Responsabile Scientifico
Nationally funded research - PRIN - NanoCARD - Nanoparticelle polimeriche ibride per una terapia a base di microRNA per la rigenerazione cardiaca: percorso di avvicinamento all’applicazione clinica (NanoCARD). , (2023-2024) - Responsabile Scientifico
Corporate-funded and donor-funded research - PACGEL - Plasma-ACtivated hydroGEL: new frontiers solutions in cardiac regenerative medicine , (2023-2025) - Responsabile Scientifico
UE-funded research - HE - Excellent Science - MSCA - SaveAR - Development of a therapeutic strategy to suppress LSD1 and PRMT6-mediated toxic gain of function in SBMA , (2023-2025) - Responsabile Scientifico
Non-EU international research - POLHYGENTH - Nanoparticelle polimeriche ibride per una nuova generazione di vettori non virali per terapia genica nella rigenerazione cardiaca (POLHYGENTH). , (2022-2023) - Responsabile Scientifico
Corporate-funded and donor-funded research - Visco3DCell- Sviluppo di una Metodologia non-Invasiva per lo studio delle proprietà Viscoelastiche di Colture Cellulari 3D. , (2021-2022) - Responsabile Scientifico
Corporate-funded and donor-funded research - BIORECAR - Direct cell reprogramming therapy in myocardial regeneration through an engineered multifunctional platform integrating biochemical instructive cues , (2018-2023) - Responsabile Scientifico
UE-funded research - H2020 - Excellent Science - ERC - MATERIALI BIOARTIFICIALI E SCAFFOLD BIOMIMETICI PER LA TERAPIA A BASE DI CELLULE STAMINALI NELLA RIGENERAZIONE DEL MIOCARDIO , (2012-2015) - Responsabile Scientifico
Nationally funded research - FIRB
Projects funded by commercial contracts
- Convenzione di ricerca ex art. 15 L. 241/1990 tra il Politecnico di Torino – Dipartimento di Ingegneria Meccanica e Aerospaziale (DIMEAS) e l’Università degli Studi di Torino – Dipartimento di Scienze Chirurgiche (DSC) e Dipartimento di Scienze Mediche (DSM) , (periodo sconosciuto) - Responsabile Scientifico
Departmental agreements
Supervised PhD students
- Martina Coletto. Programme in Bioingegneria E Scienze Medico-chirurgiche (39th cycle, 2023-in progress)
- Giovanni Paolo Stola. Programme in Bioingegneria E Scienze Medico-chirurgiche (38th cycle, 2022-in progress)
Research subject: Advanced therapies by bioengineering tools
Bionanotechnology Bionanotechnology Bionanotechnology - Daniele Testore. Programme in Bioingegneria E Scienze Medico-chirurgiche (37th cycle, 2021-in progress)
Research subject: Engineered microenvironment with biomimetic cues for cardiac regeneration
Nanomedicine Bionanotechnology Micro-, meso- and nanostructured materials for advanced therapies Materials, surfaces and biofabrication techniques for tissue engineering and advanced implants - Francesca Tivano. Programme in Bioingegneria E Scienze Medico-chirurgiche (37th cycle, 2022-in progress)
Research subject: Green technologies and materials for the development of eco/biocompatible systems for drug delivery
Medical Innovation and Technology Nanomedicine Bionanotechnology Micro-, meso- and nanostructured materials for advanced therapies Materials, surfaces and biofabrication techniques for tissue engineering and advanced implants Medical Innovation and Technology Nanomedicine Bionanotechnology Micro-, meso- and nanostructured materials for advanced therapies Materials, surfaces and biofabrication techniques for tissue engineering and advanced implants Medical Innovation and Technology Nanomedicine Bionanotechnology Micro-, meso- and nanostructured materials for advanced therapies Materials, surfaces and biofabrication techniques for tissue engineering and advanced implants - Elettra Ugliono. Programme in Bioingegneria E Scienze Medico-chirurgiche (37th cycle, 2021-in progress)
Research subject: Designing scaffolds for full-thickness esophageal replacement
Colorectal & Digestive Surgery Robotic surgery Medical Innovation and Technology Materials, surfaces and biofabrication techniques for tissue engineering and advanced implants Colorectal & Digestive Surgery Robotic surgery Medical Innovation and Technology Materials, surfaces and biofabrication techniques for tissue engineering and advanced implants Colorectal & Digestive Surgery Robotic surgery Medical Innovation and Technology Materials, surfaces and biofabrication techniques for tissue engineering and advanced implants - Letizia Nicoletti. Programme in Bioingegneria E Scienze Medico-chirurgiche (36th cycle, 2020-in progress)
Research subject: NEW ADVANCED THERAPIES FOR DRUG DELIVERY IN CARDIAC REGENERATION
Cardiac and Vascular Surgery Nanomedicine Bionanotechnology Cardiac and Vascular Surgery Nanomedicine Bionanotechnology - Roberta Pappalardo. Programme in Bioingegneria E Scienze Medico-chirurgiche (36th cycle, 2020-in progress)
Research subject: Design of injectable hydrogels as platform for in situ drug delivery and tissue engineering
Bionanotechnology Materials, surfaces and biofabrication techniques for tissue engineering and advanced implants Bionanotechnology Materials, surfaces and biofabrication techniques for tissue engineering and advanced implants Bionanotechnology Materials, surfaces and biofabrication techniques for tissue engineering and advanced implants - Gerardina Ruocco. Programme in Bioingegneria E Scienze Medico-chirurgiche (36th cycle, 2020-in progress)
Research subject: ENGINEERED BIOMIMETIC MICROENVIRONMENTS FOR THE IN VITRO ASSESSMENT OF NEW ADVANCED THERAPIES
Bionanotechnology Cardiovascular Engineering Materials, surfaces and biofabrication techniques for tissue engineering and advanced implants Bionanotechnology Cardiovascular Engineering Materials, surfaces and biofabrication techniques for tissue engineering and advanced implants - Mattia Spedicati. Programme in Bioingegneria E Scienze Medico-chirurgiche (36th cycle, 2020-in progress)
Research subject: Development of biomimetic scaffolds for in vitro modelling and tissue regeneration
Medical Innovation and Technology Nanomedicine Bionanotechnology Cardiovascular Engineering Micro-, meso- and nanostructured materials for advanced therapies Materials, surfaces and biofabrication techniques for tissue engineering and advanced implants Medical Innovation and Technology Nanomedicine Bionanotechnology Cardiovascular Engineering Micro-, meso- and nanostructured materials for advanced therapies Materials, surfaces and biofabrication techniques for tissue engineering and advanced implants
Other activities and projects related to research
COORDINATION OF RESEARCH PROJECTS
1. PROJECT ERC-CoG 2017: BIORECAR (contract number: 772168) “Direct cell reprogramming therapy in myocardial regeneration through an engineered multifunctional platform integrating biochemical instructive cues” (2018-2023). www.biorecar.polito.it
2. Project BIOMODE “In Vitro Experimental Models for Biomaterials-Mediated Drug Delivery to the Central Nervous System” - Compagnia di San Paolo (2017-2021). In collaboration with Prof. R.D. Kamm, Massachussets – MIT.
3. Project “Proof of concepts” Compagnia di San Paolo: “Method for the preparation of cellularised constructs based on thermosensitive hydrogels” (2017).
4. Project PAD-INJ “Smart Injectable Drug-Delivery systems for Parkinson’s and Alzheimer’s Disease Treatment”- Compagnia di San Paolo (2014-2016). In collaboration with Prof. M.G. Spillantini, University of Cambridge (UK).
5. Project FIRB 2010: STARIGEN “Bioartificial materials and biomimetic scaffolds for a stem cells-based therapy for myocardial regeneration” (2012-2015). Overall budget: €1.062.600 (financed grant: € 835.620).
6. Project MITOR - Compagnia di San Paolo: NANOCAB “In Vitro Modelling of Nanoparticle-Mediated Drug Delivery to the Central Nervous System by a Microfluidic Platform Mimicking the Biological Barriers” (2016-2017).
7. Project of Finalized Sanitary Research – 2008 bis, PIEDMONT REGION: “Nano-structured biomimetic coatings for regenerative medicine” (2008-2009)
8. Project of Finalized Sanitary Research – 2009, PIEDMONT REGION: “Multifunctional nano-coatings for medical devices with improved anti-inflammatory and antibacterial properties” (2009-2011).
PARTICIPATION TO RESEARCH PROJECTS
1. PROJECT CRT Visco3DCell (2021-2023). Budget: € 33.000. Role: Collaborator.
2. 2020-NMBP-TR-IND-2018 - Project EVPRO (2019-2022); € 500.000. Role: Task Leader. http://www.evpro-implant.eu/
3. H2020-MSCA ITN-2014 - Project HyMedPoly (2015-2018). Role: WP Leader. https://hymedpoly.eu/
4. BANDO ATENEO-CSP 2014 PROJECT -BIOSURF (2015-2017). Role: Unit Leader.
Publications
PoliTO co-authors
Last years publications
Publications by type
Latest publications View all publications in Porto@Iris
- Visone, Roberta; Paoletti, Camilla; Cordiale, Alessandro; Nicoletti, Letizia; Divieto, ... (2024)
In vitro mechanical stimulation to reproduce the pathological hallmarks of human cardiac fibrosis on a beating chip and predict the efficacy of drugs and advanced therapies. In: ADVANCED HEALTHCARE MATERIALS. ISSN 2192-2659
Contributo su Rivista - Paoletti, Camilla; Nicoletti, Letizia; Marcello, Elena; Zoso, Alice; Stola, GIOVANNI ... (2023)
Injectable hydrogels loaded with hybrid nanoparticles for cell/tissue specific microRNA delivery: towards novel advanced therapies for cardiac regeneration. In: 33rd Annual Conference of the European Society for Biomaterials, Davos (CH), September, 4-8, 2023
Contributo in Atti di Convegno (Proceeding) - Marcello, Elena; Nicoletti, Letizia; Paoletti, Camilla; Stola, GIOVANNI PAOLO; Chiono, ... (2023)
Self-healing and injectable alginate-based hydrogel for microRNA delivery to promote cardiac regeneration after myocardial infarction. In: International N.I.C.E. RENDEZ-VOUS 2023, Nice/Online, 20-22 Giugno 2023
Contributo in Atti di Convegno (Proceeding) - Marcello, Elena; Stola, GIOVANNI PAOLO; Paoletti, Camilla; Nicoletti, Letizia; Chiono, ... (2023)
Time-dependent natural polymer-based bioinks for cardiac tissue engineering. In: Congresso Nazionale Società Italiana Biomateriali SIB 2023, Camerino, 3-6 Luglio
Contributo in Atti di Convegno (Proceeding) - Stola, Giovanni Paolo; Marcello, Elena; Paoletti, Camilla; Nicoletti, Letizia; Chiono, ... (2023)
Natural polymer-based bioinks exploiting internal gelation mechanism for cardiac tissue engineering. In: VIII Congress of the National Group of Bioengineering (GNB), pp. 515-517. ISBN: 9788855580113
Contributo in Atti di Convegno (Proceeding) - Tivano, Francesca; Chiono, Valeria (2023)
Zein as a renewable material for the preparation of green nanoparticles for drug delivery. In: FRONTIERS IN BIOMATERIALS SCIENCE, vol. 2, pp. 01-21. ISSN 2813-3749
Contributo su Rivista - Ruocco, Gerardina; Zoso, Alice; Mortati, Leonardo; Carmagnola, Irene; Chiono, Valeria (2023)
Biomimetic Electrospun Scaffold-Based In Vitro Model Resembling the Hallmarks of Human Myocardial Fibrotic Tissue. In: ACS BIOMATERIALS SCIENCE & ENGINEERING. ISSN 2373-9878
Contributo su Rivista - Laurano, Rossella; Boffito, Monica; Cassino, Claudio; Midei, Ludovica; Pappalardo, ... (2023)
Thiol-Ene Photo-Click Hydrogels with Tunable Mechanical Properties Resulting from the Exposure of Different -Ene Moieties through a Green Chemistry. In: MATERIALS, vol. 16. ISSN 1996-1944
Contributo su Rivista - Marcello, Elena; Chiono, Valeria (2023)
Biomaterials-Enhanced Intranasal Delivery of Drugs as a Direct Route for Brain Targeting. In: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 24. ISSN 1422-0067
Contributo su Rivista - Paoletti, Camilla; Divieto, Carla; Chiono, Valeria (2023)
Direct Reprogramming of Adult Human Cardiac Fibroblasts into Induced Cardiomyocytes Using miRcombo. In: Cardiac Gene Therapy: Methods and Protocols / S.N., S.L., Springer Nature, pp. 31-40. ISBN: 978-1-0716-2707-5
Contributo in Volume - Ciofani, Gianni; Campisi, Marco; Mattu, Clara; D Kamm, Roger; Chiono, Valeria; ... (2023)
Roadmap on Nanomedicine for the Central Nervous System - Section 2: Microphysiological systems for preclinical testing of drug-loaded nanoparticle transport across the human blood-brain barrier. In: JPHYS MATERIALS, pp. 5-10. ISSN 2515-7639
Contributo su Rivista - Laurano, Rossella; Boffito, Monica; Cassino, Claudio; Liberti, Francesco; Ciardelli, ... (2023)
Design of Injectable Bioartificial Hydrogels by Green Chemistry for Mini-Invasive Applications in the Biomedical or Aesthetic Medicine Fields.. In: GELS, vol. 9, pp. 1-23. ISSN 2310-2861
Contributo su Rivista - Nicoletti, Letizia; Marcello, Elena; Paoletti, Camilla; Zoso, Alice; Stola, GIOVANNI ... (2023)
Injectable self‐healing hydrogel delivering microRNAs‐loaded nanocarriers as a promising advanced therapy for cardiac regeneration. In: TISSUE ENGINEERING, PART A. ISSN 1937-3341
Contributo su Rivista - Tivano, Francesca; Spedicati, Mattia; Zoso, Alice; Bei, Janira; Lavella, Mario; ... (2022)
3D bioartificial stretchable scaffolds for an in vitro model of fibrotic cardiac tissue. In: International Conference on Biofabrication 2022, Montecatini-Terme (IT), September 25th -28th 2022
Contributo in Atti di Convegno (Proceeding) - Tarricone, Giulia; Carmagnola, Irene; Chiono, Valeria (2022)
Tissue-Engineered Models of the Human Brain: State-of-the-Art Analysis and Challenges. In: JOURNAL OF FUNCTIONAL BIOMATERIALS, vol. 13. ISSN 2079-4983
Contributo su Rivista - Cassa, Maria Antonia; Maselli, Martina; Zoso, Alice; Chiono, Valeria; Fracchia, Letizia; ... (2022)
Development of an Innovative Soft Piezoresistive Biomaterial Based on the Interconnection of Elastomeric PDMS Networks and Electrically-Conductive PEDOT:PSS Sponges. In: JOURNAL OF FUNCTIONAL BIOMATERIALS, vol. 13. ISSN 2079-4983
Contributo su Rivista - Spedicati, Mattia; Ruocco, Gerardina; Zoso, Alice; Mortati, Leonardo; Lapini, Andrea; ... (2022)
Biomimetic design of bioartificial scaffolds for the in vitro modelling of human cardiac fibrosis. In: FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, vol. 10. ISSN 2296-4185
Contributo su Rivista - Nicoletti, Letizia; Paoletti, Camilla; Tarricone, Giulia; Andreana, Ilaria; Stella, ... (2022)
Lipoplexes for effective in vitro delivery of microRNAs to adult human cardiac fibroblasts for perspective direct cardiac cell reprogramming. In: NANOMEDICINE, vol. 45. ISSN 1549-9634
Contributo su Rivista - Laurano, R.; Boffito, M.; Ciardelli, G.; Chiono, V. (2022)
Wound dressing products: A translational investigation from the bench to the market. In: ENGINEERED REGENERATION, vol. 3, pp. 182-200. ISSN 2666-1381
Contributo su Rivista - Neuhaus, W.; Reininger-Gutmann, B.; Rinner, B.; Plasenzotti, R.; Wilflingseder, D.; De ... (2022)
The Rise of Three Rs Centres and Platforms in Europe*. In: ATLA. ALTERNATIVES TO LABORATORY ANIMALS, vol. 50, pp. 90-120. ISSN 2632-3559
Contributo su Rivista - Neuhaus, W.; Reininger-Gutmann, B.; Rinner, B.; Plasenzotti, R.; Wilflingseder, D.; De ... (2022)
The Current Status and Work of Three Rs Centres and Platforms in Europe*. In: ATLA. ALTERNATIVES TO LABORATORY ANIMALS, vol. 50, pp. 381-413. ISSN 2632-3559
Contributo su Rivista - Tivano, Francesca; Spedicati, Mattia; Zoso, Alice; Lavella, Mario; Carmagnola, Irene; ... (2022)
3D bioartificial stretchable scaffolds for an in vitro model of fibrotic cardiac tissue. In: 32nd Annual Conference of the European Society for Biomaterials (ESB), Bordeaux, 4 – 8 September 2022
Contributo in Atti di Convegno (Proceeding) - Marcello, Elena; Nicoletti, Letizia; Paoletti, Camilla; Chiono, Valeria (2022)
Injectable hydrogels for microRNA delivery to promote direct cell reprogramming in cardiac regeneration. In: 32nd Anuual Conference of the European Society for Biomaterials ESB 2022, Bordeaux, 4-8 Settembre
Contributo in Atti di Convegno (Proceeding) - Stola, GIOVANNI PAOLO; Marcello, Elena; Paoletti, Camilla; Nicoletti, Letizia; Chiono, ... (2022)
Alginate Dialdehyde-Gelatin based inks for bioprinting in cardiac tissue engineering. In: International Conference on Biofabrication 2022, Montecatini, 25 - 28 Settembre 2022
Contributo in Atti di Convegno (Proceeding) - Marcello, Elena; Nicoletti, Letizia; Paul, Geo; Cassino, Claudio; Marchese, Leonardo; ... (2021)
Injectable hydrogels for the delivery of miRNA-loaded lipoplexes in cardiac regeneration. In: Congresso Nazionale Biomateriali 2021, Lecce/Online, 11-14 Luglio 2021
Contributo in Atti di Convegno (Proceeding) - Chiono, Valeria; Farè, Silvia; Netti, Paolo A.; Vozzi, Giovanni (2021)
Biofabrication: an integrated bioengineering approach for the automated fabrication of biological structures for clinical and research applications. Bologna, Pàtron editore, P. 406. ISBN: 9788855535281
Libro - Spedicati, Mattia; Carmagnola, Irene; Zoso, Alice; Ruocco, Gerardina; Chiono, Valeria (2021)
3D In Vitro Model of Early-Stage Human Cardiac Fibrosis Based on Bioartificial Scaffold. In: Cell-Matrix Interaction and Mechanobiology in Regenerative Medicine, BRNO (CZ), 10-11 giugno 2021, pp. 36-36
Contributo in Atti di Convegno (Proceeding) - Spedicati, Mattia; Carmagnola, Irene; Zoso, Alice; Ruocco, Gerardina; Chiono, Valeria (2021)
3D IN VITRO MODELS OF EARLY AND LATE HUMAN CARDIAC FIBROSIS BY TUNING 3D ARCHITECTURE OF BIOARTIFICIAL SCAFFOLDS. In: Termis 6th world congress, Maastricht (NL), 15-19 novembre 2021, pp. 140-140
Contributo in Atti di Convegno (Proceeding) - Nardo, Tiziana; Chiono, Valeria; Carmagnola, Irene; Fracchia, Letizia; Ceresa, Chiara; ... (2021)
Mussel-inspired antimicrobial coating on PTFE barrier membranes for guided tissue regeneration. In: BIOMEDICAL MATERIALS, vol. 16. ISSN 1748-6041
Contributo su Rivista - Carmagnola, Irene; Nardo, Tiziana; Boccafoschi, Francesca; Chiono, Valeria (2016)
Layer-by-layer coating of stainless steel plates mediated by surface priming treatment to improve antithrombogenic properties. In: BIOMEDICAL SCIENCE AND ENGINEERING, vol. 2. ISSN 2531-9892
Contributo su Rivista
Society and Enterprise
Patents and other intellectual properties
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