Research Assistant
Department of Mechanical and Aerospace Engineering (DIMEAS)
Docente esterno e/o collaboratore didattico
Department of Mechanical and Aerospace Engineering (DIMEAS)
PhD Student (Unito)
Department of Mechanical and Aerospace Engineering (DIMEAS)
Profile
Research interests
Biography
Lorenzo Pallante (Italy, born in 1994) is currently a Postdoctoral researcher at the Department of Mechanical and Aerospace Engineering of Politecnico di Torino under the supervision of Prof. Marco Agostino Deriu. Mr Lorenzo Pallante received his B.Sc. in Biomedical Engineering from Politecnico di Torino (Turin, Italy) in 2016 after an undergraduate internship aimed at creating and characterizing nanofibrous membranes for regenerative medicine. In 2019, he received his M.Sc. cum laude in Biomedical Engineering from Politecnico di Torino (Turin, Italy). During his master thesis, titled “Human Tubulin Conformational Dynamics and Global Correlations Driven by Colchicine Binding”, he has investigated the conformational changes of several human tubulin isotypes induced by the presence of colchicine through molecular modelling tools. From June to October 2019, he continued his research as a research fellow at Politecnico di Torino. Since November 2019, he is enrolled in a joint PhD programme of the University of Turin and the Politecnico di Torino in Bioengineering and Medical-Surgical Sciences focused on the molecular basis of subcellular mechanics, investigated using computational modelling techniques, e.g. molecular dynamics, ensemble molecular docking, metadynamics, free energy calculations, rational drug design, and machine learning. In 2023, he completed the defence of his PhD thesise and started his activity as Postdoctoral researcher, which is still ongoing. His research primarily centers on unraveling the molecular mechanisms governing supra-molecular and cellular phenomena to gain insights into both physiological and pathological conditions. Within his research scope, he delves into exploring critical molecular players in taste perception, including taste receptors. Additionally, he applies machine learning techniques to predict the properties of food ingredients and the taste of compounds based on their chemical structures. He has practical experience with bash scripting, Python, C and MATLAB, and speaks fluent Italian and English. He is also the author of 11 papers on peer-reviewed journals and has participated in several international conferences also as a speaker.
Scientific branch
(Area 0009 - Industrial and information engineering)
Skills
ERC sectors
SDG
Teaching
Teachings
Master of Science
- Biomechanical design. A.A. 2023/24, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Rational Drug Design: Principles and Applications. A.A. 2023/24, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Biomeccanica multiscala. A.A. 2023/24, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Biomechanical design. A.A. 2022/23, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Rational Drug Design: Principles and Applications. A.A. 2022/23, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Biomeccanica multiscala. A.A. 2022/23, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Biomechanical design. A.A. 2021/22, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Rational Drug Design: Principles and Applications. A.A. 2021/22, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Biomeccanica multiscala. A.A. 2021/22, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Biomechanical design. A.A. 2020/21, INGEGNERIA BIOMEDICA. Collaboratore del corso
Research
Research groups
Publications
PoliTO co-authors
Last years publications View all publications in Porto@Iris
- Pallante, Lorenzo; Cannariato, Marco; Vezzulli, Fosca; Lambri, Milena; Deriu, Marco A. (2024)
Artificial intelligence-driven prediction of taste perception, molecular mechanisms, and food molecule trajectory. In: SCIENCE TALKS. ISSN 2772-5693
Contributo su Rivista - Pallante, Lorenzo; Cannariato, Marco; Androutsos, Lampros; Zizzi, Eric A.; Bompotas, ... (2024)
VirtuousPocketome: a computational tool for screening protein–ligand complexes to identify similar binding sites. In: SCIENTIFIC REPORTS, vol. 14. ISSN 2045-2322
Contributo su Rivista - Ferri, Francesco; Cannariato, Marco; Deriu, Marco Agostino; Pallante, Lorenzo (2024)
Machine learning approaches to predict TAS2R receptors for bitterants. In: BIOTECHNOLOGY AND BIOENGINEERING. ISSN 0006-3592
Contributo su Rivista - Pallante, Lorenzo; Cannariato, Marco; Vezzulli, Fosca; Malavolta, Marta; Lambri, Milena; ... (2023)
Machine Learning Aided Molecular Modelling of Taste to Identify Food Fingerprints. In: EFF2023 - 4th INTERNATIONAL CONFERENCE ON ENGINEERING FUTURE FOOD
Contributo in Atti di Convegno (Proceeding) - Cannariato, Marco; Zizzi, Eric Adriano; Pallante, Lorenzo; Miceli, Marcello; Deriu, ... (2023)
Mechanical communication within the microtubule through network‑based analysis of tubulin dynamics. In: BIOMECHANICS AND MODELING IN MECHANOBIOLOGY. ISSN 1617-7959
Contributo su Rivista - Maroni, Gabriele; Pallante, Lorenzo; Di Benedetto, Giacomo; Deriu, Marco A.; Piga, ... (2022)
Informed classification of sweeteners/bitterants compounds via explainable machine learning. In: CURRENT RESEARCH IN FOOD SCIENCE, vol. 5, pp. 2270-2280. ISSN 2665-9271
Contributo su Rivista - Malavolta, Marta; Pallante, Lorenzo; Mavkov, Bojan; Stojceski, Filip; Grasso, Gianvito; ... (2022)
A survey on computational taste predictors. In: EUROPEAN FOOD RESEARCH AND TECHNOLOGY, vol. 248, pp. 2215-2235. ISSN 1438-2377
Contributo su Rivista - Pallante, Lorenzo; Korfiati, Aigli; Androutsos, Lampros; Stojceski, Filip; Bompotas, ... (2022)
Toward a general and interpretable umami taste predictor using a multi-objective machine learning approach. In: SCIENTIFIC REPORTS, vol. 12. ISSN 2045-2322
Contributo su Rivista - Pallante, L.; Malavolta, M.; Grasso, G.; Korfiati, A.; Mavroudi, S.; Mavkov, B.; ... (2021)
On the human taste perception: Molecular-level understanding empowered by computational methods. In: TRENDS IN FOOD SCIENCE & TECHNOLOGY, vol. 116, pp. 445-459. ISSN 0924-2244
Contributo su Rivista - Malavolta, Marta; Pallante, Lorenzo; Deriu, Marco Agostino (2021)
Structural and Functional Analysis of Human Bitter Taste Receptors. In: 26th Congress of the European Society of Biomechanics
Contributo in Atti di Convegno (Proceeding) - Sztandera, Krzysztof; Gorzkiewicz, Michal; Sofia Dias Martins, Ana; Pallante, Lorenzo; ... (2021)
Noncovalent Interactions with PAMAM and PPI Dendrimers Promote the Cellular Uptake and Photodynamic Activity of Rose Bengal: The Role of the Dendrimer Structure. In: JOURNAL OF MEDICINAL CHEMISTRY. ISSN 0022-2623
Contributo su Rivista - Zizzi, Eric A.; Pallante, Lorenzo; Miceli, Marcello; Sztandera, Krzysztof; Batal, ... (2021)
PAMAM and PPI dendrimers as potential anti-cancer drug carriers: a computational investigation. In: CANCERTO - NANOSCIENCE IN CANCER IMMUNOTHERAPY, March 9–11, 2021. ISBN: 978-2-88966-543-3
Contributo in Atti di Convegno (Proceeding) - Pallante, Lorenzo; Zizzi, ERIC ADRIANO; Miceli, Marcello; Grasso, Gianvito; Huczynski, ... (2021)
Understanding the molecular binding mechanism of colchicine derivatives targeting bIII human tubulin isotype. In: CANCERTO - NANOSCIENCE IN CANCER IMMUNOTHERAPY, March 9–11, 2021. ISBN: 978-2-88966-543-3
Contributo in Atti di Convegno (Proceeding) - Pallante, Lorenzo; Malavolta, Marta; Grasso, Gianvito; Deriu, MARCO AGOSTINO (2021)
Scrose-driven effects on structure-function relationships in human sweet taste receptor. In: 26th Congress of the European Society of Biomechanics, Milan (IT), July 11-14, 2021
Contributo in Atti di Convegno (Proceeding)